Biophysical Chemistry 2nd Edition

Biophysical Chemistry 2nd Edition book cover

Biophysical Chemistry 2nd Edition

Author(s): Dagmar Klostermeier (Author), Markus G. Rudolph (Author)

  • Publisher: CRC Press
  • Publication Date: September 15, 2026
  • Edition: 2nd
  • Language: English
  • Print length: 922 pages
  • ISBN-10: 1032068159
  • ISBN-13: 9781032068152

Book Description

Biophysical Chemistry explores the concepts of physical chemistry and molecular structure that underlie biochemical processes. Ideally suited for undergraduate students and scientists with backgrounds in physics, chemistry, or biology, it is also equally accessible to students and scientists in related fields as the book concisely describes the fundamental aspects of biophysical chemistry and puts them into a biochemical context.

This second edition has been fully updated throughout with novel techniques, with a new chapter on advances in cryo-electron microscopy and exciting new content throughout on big data techniques, structural bioinformatics, systems biology and interaction networks, and artificial intelligence and machine learning.

The book is organized in four parts, covering thermodynamics, kinetics, molecular structure and stability, and biophysical methods. Cross-references within and between these parts emphasize common themes and highlight recurrent principles. End of chapter problems illustrate the main points explored and their relevance for biochemistry, enabling students to apply their knowledge and to transfer it to laboratory projects.

Key Features:

  • Connects principles of physical chemistry to biochemistry
  • Emphasizes the role of organic reactions as tools for modification and manipulation of biomolecules
  • Includes a comprehensive section on the theory of modern biophysical methods and their applications

Editorial Reviews

Editorial Reviews

Review

‘The authors indicate in the preface that the main target readers of this book are undergraduate students and scientists with a background in life sciences. This is definitely the least that can be said about this impressive compilation of knowledge presented in a very attractive way, with ‘boxes’ throughout the book giving some explanation of the concepts or remarks on unexpected applications, enlightened by numerous illustrations, schemes and molecular modeling that should inspire numerous teachers.

This really is a massive and impressive book overviewing a wide field of knowledge, especially when one considers that only two authors contributed.’

– Marc Hebrant, Universite´de Lorraine, Acta Crystallographica, 2025.

About the Author

Dagmar Klostermeieris of the University of Muenster, Germany.

Markus G. Rudolphis of the Pharma Research & Early Development Division in the Roche Group, Switzerland.

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